Classes of Carcinogenic Substances
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Alkylating agents |
Hydrazines |
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a-Halo
ethers
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Hydrazine (and hydrazine salts) |
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Bis(chloromethyl) ether |
1,2-Diethylhydrazine |
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Methyl chloromethyl ether |
1,1-Dimethylhydrazine |
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Sulfonates |
1,2-Dimethylhydrazine |
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1,4-Butanediol dimethanesulfonate (myleran) |
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Diethyl sulfate |
N-Nitroso compounds |
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Dimethyl sulfate |
N-Nitrosodimethylamine |
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Ethyl methanesulfonate |
N-Nitroso-N-alkylurea |
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Methyl methanesulfonate |
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Methyl trifluoromethanesulfonate |
Aromatic amines |
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1,3-Propanesultone |
4-Aminobiphenyl |
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Epoxides
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Benzidine (4, 4'-diaminobiphenyl) |
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Ethylene oxide |
a-Naphthylamine |
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Diepoxybutane |
b-Naphthylamine |
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Epichlorohydrin |
Aniline |
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Propylene oxide |
o-Anisidine(2-methoxyaniline) |
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Styrene oxide |
2,4-Diaminotoluene |
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Aziridines |
o-Toluidine |
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Ethylenimine |
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2-methylaziridine |
Aromatic hydrocarbons |
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Diazo, azo, and azoxy compounds |
Benzene |
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4-Dimethylaminoazobenzene |
Benz[a]anthracene |
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Electrophilic alkenes and alkynes |
Benzo[a]pyrene |
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Acrylonitrile |
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Acrolein |
Natural products (including antitumor
drugs) |
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Ethyl acrylate |
Adriamycin |
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Aflatoxins |
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Acylating agents |
Bleomycin |
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b-Propiolactone |
Cisplatin |
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b-Butyrolactone |
Progesterone |
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Dimethylcarbamyl chloride |
Reserpine |
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Safrole |
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Organohalogen compounds |
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1,2-Dibromo-3-chloropropane |
Miscellaneous organic compounds |
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Mustard gas (bis(2-chloroethyl)sulfide) |
Formaldehyde (gas) |
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Vinyl chloride |
Acetaldehyde |
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Carbon tetrachloride |
1,4-Dioxane |
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Chloroform |
Ethyl carbamate (uret |
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3-Chloro-2-methylpropene |
Hexamethylphosphor |
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1,2-Dibromoethane |
2-Nitropropane |
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1,4-Dichlorobenzene |
Styrene |
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1,2-Dichloroethane |
Thiourea |
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2,2-Dichloroethane |
Thioacetamide |
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1,3-Dichloropropene |
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Hexachlorobenzene |
Miscellaneous inorganic compounds |
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Methyl iodide |
Arsenic and certain arsenic compounds |
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Tetrachloroethylene |
Chromium and certain chromium compounds |
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Trichloroethylene |
Thorium dioxide |
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2,4,6-Trichlorophenol |
Beryllium and certain beryllium compounds |
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Cadmium and certain cadmium compounds |
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Lead and certain lead compounds |
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Nickel and certain nickel compounds |
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Selenium sulfide |
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From Prudent Practices in the Laboratory, National Academy
Press, 1995.